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  • On September 26, UCLA researcher reported the outcomes of a study, which indicated that Asians who will be struggling with alcoholism will benefit especially from naltrexone, considered one of three medications licensed by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation that produces them likely to benefit from naltrexone, in comparison with about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director from the UCLA Addictions Laboratory. The findings are still available online ( within the journal Neuropsychopharmacology and will also be published in an upcoming print edition of the journal.

    Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people that go through it you ought to err to the side of caution and allow FDA do its job and demand some study be done so your public is aware of the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say everything to keep people on his or her medications.

    Researchers found out that participants investing in this drug to get a year, lost weight within one month and have kept the extra weight off through the entire 56 weeks of the study. Contrave is really a combination from the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, which may make them more efficient and safer.

    Combo-pilling is the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills has become popular could be the fact that since right now there are not any long term prescription diet pills that have been licensed by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures certainly are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug may also raise blood pressure level and heart rate, and must not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure level and pulse rate and must not be used in patients with uncontrolled high blood pressure level, and also by anyone with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation.

    Most of the combinations which might be used to enhance weight loss involve an amphetamine and an antidepressant. Phentermine and Prozac can be a popular combination which were around for a while, and although it has been around my own mail to truly combine the 2 and try to get FDA approval to promote it as a weight-loss pill. Right there should raise some warning flag if the greedy pharmaceutical companies don't want to be involved in combining medications and selling them something has to be wrong with the combination. In fairness there's one weight-loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, utilized to treat alcohol and drug addiction, using the antidepressant bupropion (Wellbutrin, Zyban) it's been given the proceed to move forward by an FDA advisory committee, but since yet has not been approved.